<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Integrating Multiple Modalities of High Throughput Assays Using
Item Response Theory</dc:title>
  <dc:title>R package integIRTy version 1.0.8</dc:title>
  <dc:subject>CRAN Task View: Omics (https://CRAN.R-project.org/view=Omics)</dc:subject>
  <dc:description>Provides a systematic framework for
 integrating multiple modalities of assays profiled on the same set of
 samples. The goal is to identify genes that are altered in cancer
 either marginally or consistently across different assays. The
 heterogeneity among different platforms and different samples are
 automatically adjusted so that the overall alteration magnitude can
 be accurately inferred. See Tong and Coombes (2012) 
 &lt;doi:10.1093/bioinformatics/bts561&gt;. </dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 2.10), ltm, foreach, doParallel</dc:relation>
  <dc:relation>Imports: mclust, MASS, abind</dc:relation>
  <dc:relation>Suggests: KernSmooth</dc:relation>
  <dc:creator>Kevin R. Coombes &lt;krc@silicovore.com&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Pan Tong [aut],
  Kevin R. Coombes [aut, cre]</dc:contributor>
  <dc:rights>Apache License (== 2.0)</dc:rights>
  <dc:date>2025-04-08</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=integIRTy</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.integIRTy</dc:identifier>
</oai_dc:dc>
