babelmixr2: Use 'nlmixr2' to Interact with Open Source and Commercial Software

Run other estimation and simulation software via the 'nlmixr2' (Fidler et al (2019) <doi:10.1002/psp4.12445>) interface including 'PKNCA', 'NONMEM' and 'Monolix'. While not required, you can get/install the 'lixoftConnectors' package in the 'Monolix' installation, as described at the following url <>. When 'lixoftConnectors' is available, 'Monolix' can be run directly instead of setting up command line usage.

Version: 0.1.2
Depends: R (≥ 3.5), nlmixr2 (≥ 2.0.8)
Imports: checkmate, cli, digest, lotri, nlmixr2est (≥ 2.1.6), nonmem2rx (≥ 0.1.3), methods, qs, rex, rxode2
LinkingTo: Rcpp, rxode2, RcppArmadillo, RcppEigen, rxode2parse
Suggests: testthat, nlmixr2data, withr, lixoftConnectors, PKNCA (≥ 0.10.0), knitr, rmarkdown, spelling, units
Published: 2023-12-12
DOI: 10.32614/CRAN.package.babelmixr2
Author: Matthew Fidler ORCID iD [aut, cre], Bill Denney ORCID iD [aut], Nook Fulloption [ctb] (goldfish art)
Maintainer: Matthew Fidler <matthew.fidler at>
License: GPL (≥ 3)
NeedsCompilation: yes
Language: en-US
Citation: babelmixr2 citation info
Materials: README NEWS
In views: MixedModels
CRAN checks: babelmixr2 results


Reference manual: babelmixr2.pdf
Vignettes: Creating a New Estimation Method
Obtain initial estimates and unit conversions with PKNCA


Package source: babelmixr2_0.1.2.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): babelmixr2_0.1.2.tgz, r-oldrel (arm64): babelmixr2_0.1.2.tgz, r-release (x86_64): babelmixr2_0.1.2.tgz, r-oldrel (x86_64): babelmixr2_0.1.2.tgz
Old sources: babelmixr2 archive


Please use the canonical form to link to this page.